At the Radboud University Nijmegen, there is a vacancy for a PhD student on
the subject
NMR data analysis in metabolomics
The project is a cooperation of the laboratories of Pediatrics and Neurology
(prof. Wevers, Radboud University Nijmegen Medical Centre) and Analytical
Chemistry / Chemometrics (prof. Buydens, Institute of Molecules and
Materials, Radboud University Nijmegen).
Complex data are currently being measured at an ever increasing rate, to the
extent that the data analysis has become the rate-limiting step.
The PhD student in this project will set up and improve data analysis
strategies, using chemometrics and multivariate statistics, to analyse large
numbers of NMR spectra of patients with metabolic diseases. The aims of the
analyses include quality control, biomarker identification, and disease
classification.
The candidate should have an MSc in the life sciences, chemistry, or a
related discipline, with a demonstrable interest in data analysis;
alternatively, candidates with a background in applied statistics, with an
interest in the natural sciences, are considered as well.
Knowledge of NMR and metabolomics, as well as experience in Matlab or R, are
strong points.
The Laboratory of Pediatrics and Neurology is a mixed function laboratory
(patient care and research) of the University Medical Centre St Radboud in
Nijmegen. The laboratory is specialized in genetic and metabolic disease. It
uses proton NMR spectroscopy of body fluids to find a diagnosis in children
with metabolic disorders and applies a metabolomics strategy to find
biomarkers for specific diseases and to unravel their etiological
background.
The Department of Analytical Chemistry / Chemometrics specializes in
multivariate data analysis spectroscopic and chromatographic data. It
is involved in several national and international research projects,
both with academia and industry. More information about the department
can be found at http://www.ru.nl/science/analyticalchemistry/